NASDAQ: ALNY - Alnylam Pharmaceuticals, Inc.

Rentabilidad a seis meses: -3.1%
Rendimiento de dividendos: 0.00%
Sector: Healthcare

Calendario de promoción Alnylam Pharmaceuticals, Inc.

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Acerca de la empresa Alnylam Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc., биофармацевтическая компания, занимается открытием, разработкой и коммерциализацией терапевтических средств РНК-интерференции (РНКи). Линия исследуемых РНКи-терапевтических средств компании сосредоточена на генетических лекарствах, сердечно-метаболических заболеваниях, инфекционных заболеваниях печени и заболеваниях центральной нервной системы (ЦНС) / глаз.

más detalles
Продаваемые на рынок продукты включают ONPATTRO (патисиран), инъекцию липидного комплекса для лечения полинейропатии наследственного транстиретин-опосредованного амилоидоза у взрослых; GIVLAARI для лечения взрослых с острой печеночной порфирией (AHP); и OXLUMO (люмасиран) для лечения первичной гипероксалурии типа 1 (PH1). Кроме того, компания разрабатывает гивосиран для лечения пациентов подросткового возраста с AHP; люмасиран для лечения прогрессирующих PH1 и рецидивирующих почечных камней; патисиран для лечения транстиретинового амилоидоза или амилоидоза ATTR при кардиомиопатии; и вутрисиран для лечения амилоидоза ATTR. Alnylam Pharmaceuticals, Inc. имеет стратегическое сотрудничество с Regeneron Pharmaceuticals, Inc. для открытия, разработки и коммерциализации терапевтических средств с РНКи для ряда заболеваний путем воздействия на терапевтические цели, выраженные в глазах и ЦНС; и Sanofi Genzyme для открытия, разработки и коммерциализации терапевтических средств с РНКи. Он также имеет лицензионные соглашения и соглашения о сотрудничестве с Novartis AG для разработки, производства и коммерциализации терапевтических средств с РНКи для лечения пропротеинконвертазы субтилизин / кексин типа 9, гиперхолестеринемии и других заболеваний человека; с Vir Biotechnology, Inc. для разработки и коммерциализации терапевтических средств РНКи для лечения SARS-CoV-2, вируса, вызывающего заболевание COVID-19; Dicerna Pharmaceuticals, Inc. для разработки и коммерциализации исследуемых терапевтических средств с РНКи для лечения заболеваний печени, связанных с дефицитом альфа-1-антитрипсина; и с Ionis Pharmaceuticals, Inc. Компания была основана в 2002 году, ее штаб-квартира находится в Кембридже, Массачусетс.
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IPO date 2004-05-28
ISIN US02043Q1076
Industry Biotechnology
Sector Health Care
Валюта usd
Валюта отчета usd
Див.доход ао 0
Сайт http://www.alnylam.com
Цена ао 265.96
Cambio de precio por día: 0% (265.96)
Cambio de precio por semana.: -4.42% (278.25)
Cambio de precio por mes: +10.58% (240.51)
Cambio de precio en 3 meses.: +3.12% (257.91)
Cambio de precio en seis meses: -3.1% (274.48)
Cambio de precio por año: +80.4% (147.43)
Cambio de precio en 3 años.: +63.9% (162.27)
Cambio de precio en 5 años.: +120.31% (120.72)
Cambio de precio en 10 años.: 0% (265.96)
Cambio de precio desde principios de año.: +12.69% (236.01)
Todos los parámetros

Subestimación

Nombre Significado Calificación
P/S 13.05 1
P/BV -108.14 0
P/E 0 0
EV/EBITDA -112.79 0
Total: 1.38

Eficiencia

Nombre Significado Calificación
ROA, % -11.49 0
ROE, % 199.53 10
Total: 3.33

Dividendos

Nombre Significado Calificación
Div yield, % 0 0
DSI 0 0
Total: 0

Deber

Nombre Significado Calificación
Debt/EBITDA -4.9 10
Total: 9.2

Impulso de crecimiento

Nombre Significado Calificación
Rentabilidad Revenue, % 731.8 10
Rentabilidad Ebitda, % -72.51 0
Rentabilidad EPS, % -56.54 0
Total: 2
Más detalles

Fecha de transacción fecha de divulgación Persona enterada Tipo Precio Volumen Cantidad Comparte hasta, % compartir después, % Documento
27.01.2025 27.01.2025 Garg Pushkal
Officer		 Compra 285 14 988 700 52592 0 0.04 enlace
12.08.2024 12.08.2024 Fitzgerald Kevin Joseph
Officer		 Compra 269.52 5 936 180 22025 0 0.02 enlace
01.08.2024 02.08.2024 Greenstreet Yvonne
Chief Executive Officer		 Venta 270 4 089 960 15148 0 -0.01 enlace
01.08.2024 02.08.2024 Greenstreet Yvonne
Chief Executive Officer		 Compra 85 1 287 580 15148 0 0.01 enlace
11.07.2024 12.07.2024 Greenstreet Yvonne
Chief Executive Officer		 Venta 261 1 851 270 7093 0 -0.01 enlace
25.06.2024 27.06.2024 SCHULMAN AMY W
Director		 Venta 240 2 040 000 8500 0 -0.01 enlace
25.06.2024 27.06.2024 SCHULMAN AMY W
Director		 Compra 131.21 1 115 280 8500 0 0.01 enlace
13.05.2021 17.05.2021 MARAGANORE JOHN
Chief Executive Officer		 Venta 130.78 4 443 770 33979 0 -0.03 enlace
13.05.2021 17.05.2021 MARAGANORE JOHN
Chief Executive Officer		 Compra 7.1 241 251 33979 0 0.03 enlace

Instituciones Volumen Compartir, %
Capital World Investors 16174563 12.84
Vanguard Group Inc 11943895 9.48
FMR, LLC 10312356 8.19
Blackrock Inc. 8521115 6.77
Wellington Management Group, LLP 7214198 5.73
Baillie Gifford and Company 6967097 5.53
Dodge & Cox Inc 3674310 2.92
Capital International Investors 3586657 2.85
Price (T.Rowe) Associates Inc 3483969 2.77
T. Rowe Price Investment Management, Inc. 3426063 2.72

ETF Compartir, % Rentabilidad del año, % Dividendos, %
Global X Genomics & Biotechnology ETF 6.64287 2.58 0.15585
Direxion Daily Healthcare Bull 3x Shares 6.39499 650.74 0.09258
Direxion mRNA ETF 6.32 0
Amplify Treatments Testing and Advancements ETF 5.56 10.31 1.06
Tema Obesity & Cardiometabolic ETF 5.30214 27
Invesco Biotechnology & Genome ETF 4.90205 26.49 0.16298
Tema Neuroscience and Mental Health ETF 4.10467 0
VictoryShares Nasdaq Next 50 ETF 3.6052 25.65 0.64752
Future Tech ETF 3.41115 426.34 0.8416
Principal Healthcare Innovators ETF 3.41115 618.5 0.8416
Innovator IBD 50 ETF 3.40328 31.06 0.08939
Invesco Nasdaq Biotechnology ETF 3.38186 28.58 0.8565
Future Health ETF 3.35279 20.76
First Trust NYSE Arca Biotechnology Index Fund 3.26554 16.92 0.26101
iShares Biotechnology ETF 3.09265 1.11 0.64399
SPDR S&P Biotech ETF 2.8816 3.59 0.33232
American Century Focused Dynamic Growth ETF 2.5333 51.92 0.16246
Virtus LifeSci Biotech Products ETF 2.50178 36.79 0.13953
First Trust Health Care AlphaDEX Fund 2.40936 6.5 0.99486
iShares Evolved U.S. Innovative Healthcare ETF 2.36 0.000586 2.79
Invesco NASDAQ Next Gen 100 ETF 2.32224 26.94 0.79805
ProShares Ultra Nasdaq Biotechnology 2.29498 51.7 0.85651
Motley Fool Next Index ETF 1.98092 23.87 0.61129
Direxion Daily S&P Biotech Bull 3x Shares 1.8669 4067.92 0.25924
GraniteShares XOUT U.S. Large Cap ETF 1.82011 -4.52 0.28223
Franklin Genomic Advancements Fund Franklin Genomic Advancements Fund 1.75848 1.54 0.22433
Goldman Sachs Future Health Care Equity ETF 1.62905 16.15 0.84646
ProShares UltraShort Nasdaq Biotechnology 1.6 -40.36 1.76
WisdomTree BioRevolution Fund 1.56336 -4.69 0.78691
ROBO Global Healthcare Technology and Innovation ETF 1.50826 19.56 0.37496
Invesco ESG NASDAQ Next Gen 100 ETF 1.45157 28.11 0.73691
American Century Mid Cap Growth Impact 1.38408 35.07 0.5636
Capital Group Growth ETF 1.25454 39.4 0.71675
iShares Russell Mid-Cap Growth ETF 1.0996 29.59 0.69551
First Trust Lunt U.S. Factor Rotation ETF 0.99453 24.39 1.12012
Vanguard Mid-Cap Growth ETF 0.93 24.69 0.85744
Fidelity Women's Leadership ETF 0.89751 26.3 1.1649
iShares Exponential Technologies ETF 0.75936 5.87 1.22275
Fidelity Growth Opportunities ETF 0.72817 32.75 0.48881
iShares Morningstar Mid-Cap Growth ETF 0.63851 477.51 0.94237
iShares Morningstar Mid-Cap Growth ETF 0.63851 31.01 0.94237
Amplify Etho Climate Leadership U.S. ETF 0.60707 22.79 1.41942
Fidelity MSCI Health Care Index ETF 0.51656 3 1.46057
Vanguard Extended Market ETF 0.47 24.2 1.34786
Amplify AI Powered Equity ETF 0.41424 30.98 1.68509
Vanguard Mid-Cap ETF 0.41 20.88 1.65052
Rayliant Quantitative Developed Market Equity ETF 0.39331 36.57 1.6333
First Trust Large Cap Growth AlphaDEX Fund 0.38792 30.76 1.01462
iShares ESG MSCI USA Min Vol Factor ETF 0.3353 22.95 1.82337
IQ U.S. Large Cap R&D Leaders ETF 0.33267 30.2 1.46506
iShares Morningstar Mid-Cap ETF 0.31821 280.37 1.7458
iShares Morningstar Mid-Cap ETF 0.31821 29.74 1.7458
iShares Russell Midcap ETF 0.29722 20.77 1.71565
iShares MSCI USA Size Factor ETF 0.29176 18.09 1.87959
iShares MSCI USA Min Vol Factor ETF 0.25333 14 1.75872
First Trust Active Factor Large Cap ETF 0.23994 35.7 1.67411
John Hancock Multifactor Mid Cap ETF 0.22247 20.65 1.52586
Goldman Sachs Equal Weight U.S. Large Cap Equity ETF 0.21466 21.07 1.78003
First Trust Multi Cap Growth AlphaDEX Fund 0.18953 41.56 1.02425
First Trust Large Cap Core AlphaDEX Fund 0.18949 21.2 1.90065
Xtrackers Net Zero Pathway Paris Aligned US Equity ETF 0.18814 31.3 1.42468
SPDR S&P Kensho New Economies Composite ETF 0.18427 21.57 0.88486
iShares MSCI Global Sustainable Development Goals ETF 0.18132 1.07 2.10797
iShares ESG Advanced MSCI USA ETF 0.17588 39.78 1.23301
iShares MSCI USA ESG Select ETF 0.16949 23.65 1.52994
iShares MSCI USA Equal Weighted ETF 0.15951 27.5 1.80633
iShares Morningstar Large-Cap Growth ETF 0.14211 304.17 0.5823
iShares Morningstar Growth ETF 0.14211 37.98 0.5823
First Trust Nasdaq BuyWrite Income ETF 0.142 7.27 0.92977
Invesco Russell 1000 Equal Weight ETF 0.13702 16.58 2.1901
JPMorgan Carbon Transition U.S. Equity ETF 0.13209 25.53 1.26506
IQ Candriam ESG U.S. Large Cap Equity ETF 0.12931 28.93 1.44565
SPDR MSCI USA Gender Diversity ETF 0.12781 31.2 1.66855
Schwab U.S. Large-Cap Growth ETF 0.12604 33.66 0.51173
Convergence Long/Short Equity ETF 0.12211 32.85 1.56428
SPDR MSCI USA Climate Paris Aligned ETF 0.117 30.73 1.24803
iShares Russell 1000 Growth ETF 0.1122 31.85 0.68889
Vanguard Russell 1000 Growth ETF 0.11 31.62 0.68737
QRAFT AI Enhanced U.S. Large Cap ETF 0.10744 31.16 1.25914
Humankind US Stock ETF 0.09632 18.81 1.99919
American Century U.S. Quality Growth ETF 0.08714 39.48 0.64905
Fidelity Blue Chip Growth ETF 0.08185 39.34 0.54012
Goldman Sachs JUST U.S. Large Cap Equity ETF 0.07674 32.31 1.46271
Dimensional US Core Equity Market ETF 0.07256 30.98 1.40618
John Hancock Multifactor Large Cap ETF 0.0715 21.77 1.59539
Goldman Sachs MarketBeta U.S. Equity ETF 0.07086 25.68 1.42124
Vanguard Large Cap ETF 0.07 31.69 1.41978
Vanguard ESG U.S. Stock ETF 0.07 23.54 1.26927
Global X Adaptive U.S. Risk Management ETF 0.06953 19.25 1.41275
JPMorgan BetaBuilders U.S. Equity ETF 0.06948 25.48 1.42604
Invesco MSCI USA ETF 0.06946 25.82 1.43215
BNY Mellon US Large Cap Core Equity ETF 0.06829 31.99 1.41823
iShares Morningstar U.S. Equity ETF 0.06824 31.96 1.41244
iShares Morningstar Large-Cap ETF 0.06824 257.57 1.41244
iShares Genomics Immunology and Healthcare ETF 0.06816 -70.08 1.54385
Schwab U.S. Large-Cap ETF 0.06804 25.52 1.42733
Schwab 1000 Index ETF 0.0661 25.15 1.42441
iShares Dow Jones U.S. ETF 0.06565 25.05 1.41797
Goldman Sachs MarketBeta U.S. 1000 Equity ETF 0.06551 33 1.42661
Dimensional U.S. Equity ETF 0.06413 31.53 1.3557
Columbia Research Enhanced Core ETF 0.06359 33.58 1.60295
Schwab U.S. Broad Market ETF 0.06313 24.86 1.43354
iShares Russell 3000 ETF 0.06307 24.83 1.43482
Columbia U.S. ESG Equity Income ETF 0.0616 -99.18 1.44131
Vanguard Russell 3000 ETF 0.06 31.87 1.43817
FinEx USA UCITS ETF 0.06 54.54
Vanguard Russell 1000 ETF 0.06 25.16 1.43539
WisdomTree Efficient Gold Plus Equity Strategy Fund 0.05621 46.77 1.40216
iShares MSCI Kokusai ETF 0.05446 25.89 1.97357
Xtrackers MSCI Kokusai Equity ETF 0.05253 20.65 1.971
iShares MSCI ACWI ETF 0.0509 -19.68 2.10908
iShares Factors US Growth Style ETF 0.05083 17.49 0.7035
HCM Defender 500 Index ETF 0.0505 39.68 1.34734
Goldman Sachs ActiveBeta U.S. Large Cap Equity ETF 0.04683 24.53 1.44147
FlexShares Morningstar US Market Factor Tilt Index Fund 0.04422 21.94 1.69572
iShares Russell Mid-Cap Value ETF 0.04361 18.01 2.03934
WisdomTree U.S. Efficient Core Fund 0.03995 28.71 1.39934
SPDR MSCI ACWI Climate Paris Aligned ETF 0.038 25.32 1.86415
Adasina Social Justice All Cap Global ETF 0.03638 16.32 2.09739
Dimensional U.S. Core Equity 2 ETF 0.03473 30.76 1.47098
Invesco FTSE RAFI US 1500 Small-Mid ETF 0.03157 17.58 1.75869
Avantis U.S. Equity ETF 0.02953 23.04 1.59151
iShares Russell 1000 Value ETF 0.01542 17.45 2.15361
Columbia Research Enhanced Value ETF 0.01435 28.02 2.60097
Avantis Responsible U.S. Equity ETF 0.01067 26.78 1.45257
Vanguard Russell 1000 Value ETF 0.01 17.7 2.15186
SPDR Portfolio MSCI Global Stock Market ETF 0.00852 17.99 2.19607



Supervisor Título profesional Pago año de nacimiento
Mr. Jeffrey V. Poulton M.B.A. CFO & Executive VP 972.35k 1968 (57 años)
Ms. Christine Regan Lindenboom Senior VP of Investor Relations & Corporate Communications N/A 1981 (44 año)
Dr. Akshay K. Vaishnaw M.D., Ph.D. Chief Innovation Officer & Member of the Scientific Advisory Board 1.24M 1963 (62 año)
Dr. Kevin Joseph Fitzgerald Ph.D. Senior VP, Head of Research & Chief Scientific Officer N/A 1969 (56 años)
Mr. Piyush Sharma J.D. Chief Ethics & Compliance Officer N/A
Dr. Pushkal P. Garg M.D. Chief Medical Officer 1M 1968 (57 años)
Mr. Timothy J. Maines Chief Technical Operations & Quality Officer N/A
Dr. Yvonne L. Greenstreet M.B.A., MBChB CEO & Director 2.09M 1963 (62 año)
Mr. Tolga Tanguler M.B.A. Executive VP & Chief Commercial Officer 1973 (52 año)
Mr. Evan Lippman M.B.A. Chief Corporate Development & Strategy Officer

DIRECCIÓN: United States, Cambridge, MA , 675 West Kendall Street - abrir en mapas de google, abrir mapas de Yandex
Sitio web: http://www.alnylam.com